SLU-PP-332 500MCG 30ML

Description

Non-toxic pan ERRα/β/γ agonist with significant ERRα activity that acts as an exercise mimetic.

SLU-PP-332 is a synthetic agonist of the estrogen receptor-related receptors (ERRs), a group of nuclear receptors that regulate energy metabolism. By selectively activating these receptors, SLU-PP-332 enhances the body’s natural aerobic exercise response, leading to amplified energy expenditure and accelerated fat metabolism. This compound mimics and intensifies physiological metabolic pathways typically triggered by exercise, making it a potential game-changer in metabolic health and fitness.

SLU-PP-332 is a non-toxic pan ERRα/β/γ (estrogen receptor-related receptors α/β/γ) agonist with significant ERRα activity (EC50 = 98, 230 & 430 nM against ERRα, ERRβ & ERγ) and acts as an exercise mimetic. SLU-PP-332 displays selectivity over ERα, ERβ and several other closely related nuclear receptors. It induces Ddit4 expression and enhances mitochondrial respiration in C2C12 myocytes (10 µM) and exercise endurance